Assistant Professor Department of Chemical and Biomolecular Engineering

(65) 6516 3835

E5 02-24



Google Scholar


  • PhD (Chem. and Pharm. Eng.) Singapore-MIT Alliance, 2012
  • BEng (Chem. Eng.) Tianjin University, 2007

Research Interests

  • Genetic Engineering of Microbes
  • Quantification of Cellular Metabolites
  • Fermentation Technology

Selected Publications

K. Zhou, K. Qiao, S. Edgar and G. Stephanopoulos, “Distributing a metabolic pathway among a microbial consortium enhances production of natural products.” Nat Biotechnol 2015, 33(4): 377-383 (Highlighted in Editors’ Choice in Science).

K. Zhou, R. Zou, C. Zhang, G. Stephanopoulos and H.P. Too, "Optimization of amorphadiene synthesis in bacillus subtilis via transcriptional, translational, and media modulation." Biotechnol Bioeng 2013, 110(9): 2556-2561.

K. Zhou, R. Zou, G. Stephanopoulos and H.P. Too, “Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production.” Microb Cell Fact, 2012, 11: 148.

K. Zhou, R. Zou, G. Stephanopoulos and H.P. Too, “Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production.” PLoS ONE, 2012, 7: e47513.

K. Zhou, L. Zhou, Q.E. Lim, R. Zou, G. Stephanopoulos and H.P. Too, “Novel reference genes for quantifying transcriptional responses of Escherichia coli to protein overexpression by quantitative PCR.” BMC Mol Biol 12, 2011, 18.