Dong-Yup LEE

Assistant Professor Department of Chemical and Biomolecular Engineering

(65) 6516 6907

E5 03-12

cheld@nus.edu.sg

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Education

  • PhD (Chem. & Biomolecular Eng.) KAIST, 2004
  • MSc (Chem. & Biomeolecular Eng.) KAIST, 2000
  • BSc (Chem. Eng.) Yonsei Univ., 1998

Research Interests

  • Systems Biology/Biotechnology
  • Drug & Disease Modeling and Control
  • Supply Chain Optimization
  • Health/Energy/Environmental Policy Modeling

Selected Publications

D. S.-W. Ow, D.-Y. Lee, M. G.-S. Yap and S. K.-W. Oh, "Identification of cellular objective for elucidating the physiological state of plasmid-bearing Escherichia coli using genome-scale in silico analysis", Biotechnol. Prog., in press.

J. O. Ahn, H. W. Lee, R. Saha, M. S. Park, J.-K. Jung and D.-Y. Lee, "Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions", J. Microbiol. Biotechnol., in press.

P.-J. Kim†, D.-Y. Lee†, T. Y. Kim, K. H. Lee, H. Jeong, S. Y. Lee and S. Park. "Metabolite-essentiality elucidates robustness of Escherichia coli metabolism", Proc. Natl. Acad. Sci. USA, 104(34), 13638-13642 (2007). (†Equally contributed authors)

S. Selvarasu, D.-Y. Lee and I. A. Karimi. "Identifying synergistically switching pathways for multi-product strain improvement using multiobjective flux balance analysis", Computer-Aided Chemical Engineering, 24, 1007-1012 (2007).

H. S. Choi, T. Y. Kim, D.-Y. Lee and S. Y. Lee. "Incorporating metabolic flux ratios into constraint-based flux analysis by using artificial metabolites and converging ratio determinants", J. Biotechnol., 129, 696-705 (2007).